"Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis)"

Sharma B.R.; Karki R.; Rajesh Y.; Kanneganti T.-D., The Journal of biological chemistry, 2023 Sep, 299(9), 105141

"NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs"

Sundaram B.; Pandian N.; Mall R.; Wang Y.; Sarkar R.; Kim H.J.; Malireddi R.K.S.; Karki R.; Janke L.J.; Vogel P.; Kanneganti T.-D., Cell, Jun 22, 186(13), 2783-2801

"PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis"

Karki R.; Kanneganti T.-D., Current Opinion in Immunology, 2023 Aug, 83, 102348

"ADAR1 and ZBP1 in innate immunity, cell death, and disease"

Karki R.; Kanneganti T.-D., Trends in Immunology, 2023 Mar, 44(3), 201-216

"Regulated cell death pathways and their roles in homeostasis, infection, inflammation, and tumorigenesis"

Lee, Ein#; Song, Chang-Hyun#; Bae, Sung-Jin; Ha, Ki-Tae; Karki, Rajendra∗, Experimental and Molecular Medicine, 2023 Aug, 55(8), 1632-1643

"Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology"

Mall R.; Bynigeri R.R.; Karki R.; Malireddi R.K.S.; Sharma B.R.; Kanneganti T.-D., Nucleic Acids Research Cancer, 2022, 4(4), zcac033

"Innate immunity, cytokine storm, and inflammatory cell death in COVID-19"

Karki R.; Kanneganti T.-D., Journal of translational medicine, 2022, 20(1), 542

"Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation"

Wang Y.; Karki R.; Mall R.; Sharma B.R.; Kalathur R.C.; Lee S.; Kancharana B.; So M.; Combs K.L.; Kanneganti T.-D., Cell reports, 2012 Oct, 4;41(1), 111434

"Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method"

Wang Y.; Pandian N.; Han J.-H.; Sundaram B.; Lee S.J.; Karki R.; Guy C.S.; Kanneganti T.-D., Cellular and Molecular Life Sciences, 2022 Sep 28, 79(10), 531

"ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection"

Karki R.#; Lee S.#; Mall R.; Pandian N.; Wang Y.; Sharma B.R.; Malireddi R.K.S.; Yang D.; Trifkovic S.; Steele J.A.; Connelly J.P.; Vishwanath G.; Sasikala M.; Reddy D.N.; Vogel P.; Pruett-Miller S.M.; Webby R.; Jonsson C.B.; Kanneganti T.-D., Science Immunology, 2022 Aug, 26;7(74), eabo6294

"NLRC4 Deficiency Leads to Enhanced Phosphorylation of MLKL and Necroptosis"

Sundaram B.; Karki R.; Kanneganti T.-D., Immuno Horizons, 2022 Mar, 17;6(3), 243-252

"The Transcription Factor IRF9 Promotes Colorectal Cancer via Modulating the IL-6/STAT3 Signaling Axis"

Sharma B.R.†; Karki R.†; Sundaram B.; Wang Y.; Vogel P.; Kanneganti T.-D.*, Cancers, 2022 Feb, 14(4), 919

"Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth"

R K Subbarao Malireddi#, Rajendra Karki#, Balamurugan Sundaram#, Balabhaskararao Kancharana#, SangJoon Lee, Parimal Samir, Thirumala-Devi Kanneganti, ImmunoHorizons, 2021 Jul, 21;5(7), 568-580

"AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence"

SangJoon Lee, Rajendra Karki, Yaqiu Wang, Lam Nhat Nguyen, Ravi C Kalathur, Thirumala-Devi Kanneganti, Nature, 2021 Sep, 597(7876), 415-419

"ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis"

Rajendra Karki, Balamurugan Sundaram, Bhesh Raj Sharma, SangJoon Lee, R K Subbarao Malireddi, Lam Nhat Nguyen, Shelbi Christgen, Min Zheng, Yaqiu Wang, Parimal Samir, Geoffrey Neale, Peter Vogel, Thirumala-Devi Kannegani, Cell reports, 2021 Oct, 37(3), 109858